منابع مشابه
Chlorpromazine-Induced Hyperprolactinemia on Rat’s Uterus
Background: Hyperprolactinemia is a common side effect of antipsychotic drugs that requires further investigation. The current study was designed to evaluate dose-dependent effect of chlorpromazine (CPZ) on hormonal changes and uterine horn histological structure in rats. Moreover, the mammary glands were analyzed to show hyperprolactinemia-induced histological changes. Methods: Albino Wistar r...
متن کاملEffects of Chlorpromazine on Some Motor Reflexes*~-
-The effects of chlorpromazine (CPZ) on the patellar reflex and segmentally evoked spinal cord potentials were determined in various cat preparations. CPZ in doses of I-8 mg/kg given intravenously (as an accumulative dose) produced a signiticant depression of the patellar reflex and segmentally evoked potentials in animals with an intact central nervous system. Hypotension, potentiation of anes...
متن کاملComparative studies on the EEG effects of imipramine and chlorpromazine in the normal and reserpinized rabbits.
Among a series of clinically available psychopharmacological agents chlorproma zine is known to be effective against the reactive or neurotic depressive disorders with little effect on the endogenous depression, while imipramine is described to be very effec tive against the endogenous disorders by activating the psychic processes rather than by sedating. Therefore, the comparison of the pharma...
متن کاملElectromyographic studies of effects of chlorpromazine on nociceptively and proprioceptively induced reflex pattern of rabbits hindlimb.
Numerous reports including Courvoisier et al. (1) have been made of the pharmacolo gical studies on chlorpromazine. The action of chlorpromazine on the central nervous system has been studied in reference to electroencephalography and evoked potentials from the brain of animal. Although the action mechanism of the drug has been well explained, much seems still left unclarified. The most conspic...
متن کاملStudies on the mechanism controlling growth hormone release induced by chlorpromazine in the anesthetized rat.
In intact urethane-anesthetized rats, plasma growth hormone (GH) levels were low but increased significantly following intravenous injection of chlorpromazine. Plasma GH levels were significantly elevated in rats with hypothalamic cuts such as complete deafferentiation, anterior cut and antero-lateral cut, whereas plasma GH levels in rats with posterior cut or postero-lateral cut were not sig...
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ژورنال
عنوان ژورنال: Folia Pharmacologica Japonica
سال: 1958
ISSN: 0015-5691,1347-8397
DOI: 10.1254/fpj.54.1151